I believe the answer cuts accross many different topics, but perhaps the most important is social justice. This opens up a discussion about the relationships between government, secular knowledge, economics, and governance. But, to narrow it down to a single issue, here is an example: what is the meaning of human enhancement in the context of the crcna, and what is the relationship between what God wants, what is true, and what we ought to do about it? More narrowly still, should humans 'improve' themselves, and how are we to decide what improvement is? For example, should the market decide who gets which enhancement or should God decide, and how would we know that is what God wants for us? Sorry, this is such a broad topic, but I think you get the gist of what I am asking. Any answer you give would be nice, but if you could contrast it with an answer great Christians of the past might have given (such as Descartes, or St. Augustine of Hippo) that would be very helpful. For example, if God wants us to have better vision why didn't he make us that way, or offer us advice on how to do so?